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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 395776Generated: October 27, 2026

2-Amino-1,3-thiazole-5-carboxylic acid → N1-(2-Aminothiazol-5-ylcarbonyl)-N2-(4-tert-butylbenzoyl)-1,2-benzenediamine

https://huagongshe.com/reaction/395776

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-1,3-thiazole-5-carboxylic acidHCID 315243—
ReactantN-(2-aminophenyl)-4-tert-butylbenzamideHCID 1133079—
ProductN1-(2-Aminothiazol-5-ylcarbonyl)-N2-(4-tert-butylbenzoyl)-1,2-benzenediamineHCID 5455960313%

Reaction Steps

Using the procedure described in Example 102, Part A, 2-aminothiazole-5-carboxylic acid (1.0 mmol) and N1-(4-tert-butylbenzoyl)-1,2-benzenediamine (1.5 mmol) yielded 50 mg (13%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605626B2
Source datasetuspto-grants-2003_08
ORD IDord-ba8e437fca234e11835b796add25610c
Source noteuspto-grants-2003_08