Potassium Hydroxide → HCID 18173082, compound

HRID 395884Notes

Reaction equation

HRID 395884 reaction equation
[O:1]=[C:2]1[N:10]([CH2:11][CH2:12][CH3:13])[C:9]2[N:8]=[C:7]([CH:14]3[CH2:20][CH:19]4[CH:21]([CH:22](C(O)=O)[C:23]([OH:25])=[O:24])[CH:16]([CH2:17][CH2:18]4)[CH2:15]3)[NH:6][C:5]=2[C:4](=[O:29])[N:3]1[CH2:30][CH2:31][CH3:32].[OH-].[K+]>CO>[O:1]=[C:2]1[N:10]([CH2:11][CH2:12][CH3:13])[C:9]2[N:8]=[C:7]([CH:14]3[CH2:20][CH:19]4[CH:21]([CH2:22][C:23]([OH:25])=[O:24])[CH:16]([CH2:17][CH2:18]4)[CH2:15]3)[NH:6][C:5]=2[C:4](=[O:29])[N:3]1[CH2:30][CH2:31][CH3:32]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 18173112HCID 18173112, compound

Product 1

HCID 18173082HCID 18173082, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-[3-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-bicyclo[3.2.1]oct-8-yl]-malonic acid was converted to the product by refluxing in MeOH in the presence of 1N KOH (1 ml) for 2 days. Mass (ES+403).

Sources & evidence

ORD record
ord-95502ebefab047a3bba5b5f44fb8a3bc
Source dataset
uspto-grants-2003_08
Patent number
US06605600B1

Reaction notes

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