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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396017Generated: October 28, 2026

Tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilane → HCID 10166207, compound

https://huagongshe.com/reaction/396017

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenylsilaneHCID 12045564—
ReactantHCID 18173882HCID 18173882—
SolventChloroform methanolHCID 21584188—
ProductHCID 10166207HCID 1016620711.5%

Reaction Steps

4-[4-(2-Aminoethoxy)anilino]-N-(4-fluorobenzyl)-1-piperidinecarboxamide (0.63 g, 1.4 mmol) was reacted with tert-butyl-(4-oxiranylmethoxy-phenoxy)-diphenyl-silane (0.53 g, 1.3 mmol) according to Procedure G (eluant: 20:1 chloroform-methanol) to give the title compound (0.125 g, 0.15 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06605618B2
Source datasetuspto-grants-2003_08
ORD IDord-39579c2c29a34e0892488bb2a8c88d2b
Source noteuspto-grants-2003_08