反应详情

In an analogous manner to the procedure of Example II, 2.88 g (11.20 mmol) of 5-benzyloxy-2-nitrobenzaldehyde in 30 ml of THF are reacted at −78° C. with 31.7 ml (15.67 mmol) of a 0.5 M 2-methyl-propenylmagnesium bromide soln in THF to give 1.8 g (51%) of 1-[5-(benzyloxy)-2-nitrophenyl]-3-methyl-2-buten-1-ol.