反应详情

3.67 g (42.23 mmol) of manganese dioxide are suspended in a solution of 1.58 g (5.28 mmol) of 1-[5-(benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-ol in 30 ml of dichloromethane. The suspension is heated under reflux overnight, and after cooling to room temperature the mixture is filtered through kieselguhr, the residue is washed with dichloromethane and the filtrate is concentrated in vacuo and dried. 1.34 g (85%) of 1-[5-(benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-one are obtained.

1. temperatureThe suspension is heated
2. temperatureunder reflux overnight
3. filtrationis filtered through kieselguhr
4. washthe residue is washed with dichloromethane
5. concentrationthe filtrate is concentrated in vacuo
6. customdried