1-[5-(Benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-ol → 1-[5-(Benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-one

Participants

Reaction Steps

3.67 g (42.23 mmol) of manganese dioxide are suspended in a solution of 1.58 g (5.28 mmol) of 1-[5-(benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-ol in 30 ml of dichloromethane. The suspension is heated under reflux overnight, and after cooling to room temperature the mixture is filtered through kieselguhr, the residue is washed with dichloromethane and the filtrate is concentrated in vacuo and dried. 1.34 g (85%) of 1-[5-(benzyloxy)-2-nitrophenyl]-2-methyl-2-propen-1-one are obtained.

Provenance & Evidence