HCID 21353733, compound → HCID 23003081, compound

HRID 396129Notes

Reaction equation

HRID 396129 reaction equation
C([O:8][C:9]1[CH:10]=[CH:11][C:12]([N+:22]([O-])=O)=[C:13]([C:15](=[O:21])[C:16]#[C:17][CH2:18][CH2:19][CH3:20])[CH:14]=1)C1C=CC=CC=1>C(O)C.[Pd]>[NH2:22][C:12]1[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][C:13]=1[C:15](=[O:21])[CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 1

HCID 21353733HCID 21353733, compound

Product 1

HCID 23003081HCID 23003081, compoundYield 95%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Analogously to the procedure of Example X, starting from 1.44 g (4.45 mmol) of 1-[5-(benzyloxy)-2-nitrophenyl]-2-hexin-1-one with 0.20 g of palladium/carbon (10%) in 50 ml of ethanol under hydrogen, after 3 h 874 mg (95%) of 1-(2-amino-5-hydroxyphenyl)-1-hexanone are obtained.

Sources & evidence

ORD record
ord-1eb1bc36756d43368e825aa70359a4e7
Source dataset
uspto-grants-2003_08
Patent number
US06608049B2

Reaction notes

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