HCID 86586631, compound → HCID 23003083, compound

HRID 396130Notes

Reaction equation

HRID 396130 reaction equation
C([O:8][C:9]1[CH:10]=[CH:11][C:12]([N+:20]([O-])=O)=[C:13]([C:15](=[O:19])/[CH:16]=[CH:17]\[CH3:18])[CH:14]=1)C1C=CC=CC=1>C(O)C.[Pd]>[NH2:20][C:12]1[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][C:13]=1[C:15](=[O:19])[CH2:16][CH2:17][CH3:18]

Participants

4

Reactant 1

HCID 86586631HCID 86586631, compound

Product 1

HCID 23003083HCID 23003083, compoundYield 97%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Analogously to the procedure of Example X, starting from 1.31 g (4.42 mmol) of E/Z-1-[5-(benzyloxy)-2-nitrophenyl]-2-buten-1-one with 0.17 g of palladium/carbon (10%) in 30 ml of ethanol under hydrogen, after 3 h 770 mg (97%) of 1-(2-amino-5-hydroxyphenyl)-1-butanone are obtained.

Sources & evidence

ORD record
ord-5bf06409da3c4a4aa153deef1b31876d
Source dataset
uspto-grants-2003_08
Patent number
US06608049B2

Reaction notes

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