HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178428763, compound → HCID 178428502, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178428763 | HCID 178428763 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178428502 | HCID 178428502 | 64% |
Reaction Steps
In an analogous manner to the procedure of Example 1, 172 mg (0.507 mmol) of 5-(2,6-dimethyl-4-nitrophenoxy)-3-isobutyl-1H-indazole are reacted with 25 mg of palladium/carbon (10%) in 15 ml of ethanol under hydrogen in the course of 3 h to give 100 mg (64%) of 5-(4-amino-2,6-dimethylphenoxy)-3-isobutyl-1H-indazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06608049B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-caa78f53330943c88f24114283e00315 |
| Source note | uspto-grants-2003_08 |