HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → [5-Chloro-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate | HCID 11187263 | — |
| Reactant | 2-Bromoacetyl4-methylpyridine hydrobromide | HCID 23003603 | — |
| Product | [5-Chloro-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic Acid | HCID 23003314 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 8 (Method A) from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (step 3) and 2-bromoacetyl-4-methylpyridine hydrobromide (F. H. Case et al., J. Am. Chem. Soc., 1956, 78, 5842).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06608070B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-518cf875763748a192482c955401722a |
| Source note | uspto-grants-2003_08 |