Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396443Generated: October 26, 2026

2-Bromoacetyl-1-methylimidazole hydrobromide → [6-Chloro-2-(1-methylimidazole-2-carbonyl)-1H-indol-3-yl]acetic Acid

https://huagongshe.com/reaction/396443

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoacetyl-1-methylimidazole hydrobromideHCID 22049840—
ReactantMethyl trans-4-chloro-2-(ethoxycarbonylamino)cinnamateHCID 23003310—
Product[6-Chloro-2-(1-methylimidazole-2-carbonyl)-1H-indol-3-yl]acetic AcidHCID 18542187—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 31 from methyl trans-4-chloro-2-(ethoxycarbonylamino)cinnamate (Example 31, step 1) and 2-bromoacetyl-1-methylimidazole hydrobromide.*

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-bb530a1ed0cf48999e00faa6b971a6a1
Source noteuspto-grants-2003_08