HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[5-chloro-2-(thiazole-2-carbonyl)-1h-indol-3-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate | HCID 11187263 | — |
| Reactant | 2-Bromo-1-(1,3-thiazol-2-yl)-1-ethanone hydrobromide | HCID 23003246 | — |
| Product | Methyl[5-chloro-2-(thiazole-2-carbonyl)-1h-indol-3-yl]acetate | HCID 23003575 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 8 (Method A) from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetylthiazole hydrobromide (A. Dondoni, A. Marra, and P. Merino, J. Am. Chem. Soc., 1994, 116, 3324).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06608070B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-e414640a30c04e6489dbe4e7ce09d6b9 |
| Source note | uspto-grants-2003_08 |