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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396471Generated: October 29, 2026

[6-Chloro-2-(5-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic Acid → Methyl[5-chloro-2-(5-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-Chloro-2-(5-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic AcidHCID 9862268—
ReactantMethyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 11187263—
ProductMethyl[5-chloro-2-(5-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003382—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(phenylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetyl-5-methylpyridine (Preparation is described in step 1 of Example 32).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-26744c45b1164c5aa0aa314cf260ff72
Source noteuspto-grants-2003_08