Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396480Generated: October 29, 2026

1-(4-Chloro-pyridin-2-yl)-ethanone → 2-Acetyl-4-(tert-butyldimethylsilyloxymethyl)pyridine

https://huagongshe.com/reaction/396480

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chloro-pyridin-2-yl)-ethanoneHCID 13011986—
Reactant4-(Tert-butyldimethylsilyloxymethyl)pyridinecarbonitrileHCID 14541448—
Product2-Acetyl-4-(tert-butyldimethylsilyloxymethyl)pyridineHCID 23003397—

Reaction Steps

The title compound was prepared from 4-(tert-butyldimethylsilyloxymethyl)pyridinecarbonitrile (A. Hadri et al., J. Heterocycl. Chem., 1993, 30, 631) according to the procedure for preparing 2-acetyl-4-chloropyridine described in Example 33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-f3be48cd045946b28da30988357d4806
Source noteuspto-grants-2003_08