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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396491Generated: October 30, 2026

Methyl trans 5-chloro-2-(phenylsulfonylamino)cinnamate → methyl[5-chloro-2-(4-ethyl-3-fluoropyridine-2-carbonyl)-1H-indol-3-yl]acetate

https://huagongshe.com/reaction/396491

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans 5-chloro-2-(phenylsulfonylamino)cinnamateHCID 11187263—
Reactant2-Bromoacetyl-4-ethyl-3-fluoropyridineHCID 23003426—
Productmethyl[5-chloro-2-(4-ethyl-3-fluoropyridine-2-carbonyl)-1H-indol-3-yl]acetateHCID 23003366—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-5-chloro-2-(penylsulfonylamino)cinnamate (Example 36, step 3) and 2-bromoacetyl-4-ethyl-3-fluoropyridine*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-c36dfc90731740c2ba34ed896f72c3d3
Source noteuspto-grants-2003_08