Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396502Generated: October 26, 2026

[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic Acid → Methyl[5,6-dichloro-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396502

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic AcidHCID 9862267—
ReactantMethyl trans-4,5-dichloro-2-(phenylsulfonylamino)cinnamateHCID 15453706—
ProductMethyl[5,6-dichloro-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003546—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4,5-dichloro-2-(phenylsulfonylamino)cinnamate (step 3) and 2-bromoacetyl-4-methylpyridine hydrobromide (Preparation is described in step 2 of Example 31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-2d083b93ba184b5cbc1de04825df0137
Source noteuspto-grants-2003_08