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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396503Generated: October 26, 2026

[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic Acid → Methyl[6-methoxy-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[6-Chloro-2-(4-methylpyridine-2-Carbonyl)-1H-indol-3-yl]acetic AcidHCID 9862267—
ReactantMethyl trans-4-methoxy-2-(p-toluenesulfonylamino)cinnamateHCID 23003261—
ProductMethyl[6-methoxy-2-(4-methylpyridine-2-carbonyl)-1h-indol-3-yl]acetateHCID 23003584—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-4-methoxy-2-(p-toluenesulfonylamino)cinnamate (step 3) and 2-bromoacetyl-4-methylpyridine hydrobromide (Preparation is described in step 2 of Example 31).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-9f108b98dd3e4b92a742e04d67b0a96e
Source noteuspto-grants-2003_08