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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396508Generated: October 29, 2026

2-Bromoacetyl-4-ethylpyridine → Methyl[2-(4-ethylpyridine-2-carbonyl)-5-trifluoromethoxy-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396508

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoacetyl-4-ethylpyridineHCID 23003263—
ReactantMethyl trans-2-p-toluenesulfonylamino-5-(trifluoromethoxy)cinnamateHCID 23003398—
ProductMethyl[2-(4-ethylpyridine-2-carbonyl)-5-trifluoromethoxy-1h-indol-3-yl]acetateHCID 23003375—

Reaction Steps

The title compound was prepared according to the procedure described in Example 57 from methyl trans-2-p-toluenesulfonylamino-5-(trifluoromethoxy)cinnamate (step 2 of Example 145) and 2-bromoacetyl-4-ethylpyridine (Preparation is described in Example 57).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-88e2dc5bfef94fd5999160405cf22f1c
Source noteuspto-grants-2003_08