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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396520Generated: October 29, 2026

Methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate → Methyl[6-chloro-2-[4-(methylsulfonylamino)benzoyl]-1h-indol-3-yl]acetate

https://huagongshe.com/reaction/396520

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl trans-4-chloro-2-(phenylsulfonylamino)cinnamateHCID 11371593—
ReactantN-(4-(2-bromoacetyl)phenyl)methanesulfonamideHCID 15592151—
ProductMethyl[6-chloro-2-[4-(methylsulfonylamino)benzoyl]-1h-indol-3-yl]acetateHCID 23003240—

Reaction Steps

The title compound was prepared according to the procedure described in Example 8 (Method B) from methyl trans-4-chloro-2-(phenylsulfonylamino)cinnamate (step 1 of Example 8, Method A) and 4-(methylsulfonylamino)phenacyl bromide*.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-3695724a4550449891d0cd02ae51c460
Source noteuspto-grants-2003_08