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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396568Generated: October 29, 2026

1-(4-Chloro-pyridin-2-yl)-ethanone → 2-Acetyl-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridine

https://huagongshe.com/reaction/396568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Chloro-pyridin-2-yl)-ethanoneHCID 13011986—
Reactant4-[1-(tert-Butyldimethylsilyloxy)ethyl]-2-pyridinecarbonitrileHCID 23003408—
Product2-Acetyl-4-[1-(tert-butyldimethylsilyloxy)ethyl]pyridineHCID 23003319—

Reaction Steps

The title compound was prepared from 4-[1-(tert-butyldimethylsilyloxy)ethyl]-2-pyridinecarbonitrile according to the procedure for preparing 2-acetyl-4-chloropyridine described Example 33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608070B1
Source datasetuspto-grants-2003_08
ORD IDord-8011f74b46c341db845816c13b9aed65
Source noteuspto-grants-2003_08