Trifluoroacetic acid → HCID 23004014, compound

Participants

Reaction Steps

A solution of (R/S) ethyl 3-(1-boc-2,3-dihydro-1H-indol-5-yl)butyrate (3.1 g, Reference Example 6) in dichloromethane (30 ml), cooled in an ice bath, was treated with trifluoroacetic acid (30 ml). After about 30 minutes the reaction mixture was evaporated and traces of trifluoroacetic acid were removed by chasing off with toluene (twice), to give the title compound as a dark viscous gum, which was used immediately without further purification.

Provenance & Evidence