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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 396804Generated: October 28, 2026

3-Fluoro-4-sulfamoylphenylhydrazine hydrochloride → 2-Fluoro-4-[5-[4-(2-furyl)-3-methylphenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

https://huagongshe.com/reaction/396804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-sulfamoylphenylhydrazine hydrochlorideHCID 22316669—
Reactant4,4,4-Trifluoro-1-[4-(2-furyl)-3-methylphenyl]butane-1,3-dioneHCID 22316748—
Product2-Fluoro-4-[5-[4-(2-furyl)-3-methylphenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamideHCID 22316795—

Reaction Steps

The title compound was prepared according to the procedure of Example 60 using 3-fluoro-4-sulfamoylphenylhydrazine hydrochloride instead of 3-fluoro-4-(methylsulfonyl)phenylhydrazine hydrochloride and 4,4,4-trifluoro-1-[4-(2-furyl)-3-methylphenyl]butane-1,3-dione instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione in step 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06608095B2
Source datasetuspto-grants-2003_08
ORD IDord-555bb7546e524a8ab45aa29bc2c4d847
Source noteuspto-grants-2003_08