反应详情

To a stirred solution of m-anisidine (12.3 g, 0.1 mol) in THF (80 mL) was added acetic anhydride (11.3 mL, 0.12 mol) at 0° C. The mixture was stirred at room temperature for 30 minutes. The reaction mixture was washed with water (50 mL), brine (30 mL), dried over MgSO4, and concentrated in vacuo. The resulting solid was recrystallized from methylene chloride-hexane to give the subtitle compound (15.9 g, 96.4% yield).

1. washThe reaction mixture was washed with water (50 mL), brine (30 mL)
2. dry with materialdried over MgSO4
3. concentrationconcentrated in vacuo
4. customThe resulting solid was recrystallized from methylene chloride-hexane