2-Chloroethyl methyl ether → HCID 22672664, compound

HRID 396975Notes

Reaction equation

HRID 396975 reaction equation
[CH3:1][C:2]1[N:3]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:4]2[C:13]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=[CH:6][C:5]=2[N:14]=1.[CH3:19][O:20][CH2:21]CCl>>[CH3:19][O:20][CH2:21][CH2:1][C:2]1[N:3]([CH2:15][CH:16]([CH3:18])[CH3:17])[C:4]2[C:13]3[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=[CH:6][C:5]=2[N:14]=1

Participants

3

Reactant 2

HCID 123162-Chloroethyl methyl etherHCID 13958376HCID 13958376, compound

Product 1

HCID 22672664HCID 22672664, compound

Procedure

Using the general method of Example 45, 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (2 g 8.4 mmol,) was reacted with 2-chloroethyl methyl ether (0.76 mL, 10 mmol) to provide the desired product. The structure was confirmed by nuclear magnetic resonance spectroscopy.

Sources & evidence

ORD record
ord-b550bfed07fc4db2925d088a709d3e9b
Source dataset
uspto-grants-2003_08
Patent number
US06608201B2

Reaction notes

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