HCID 90953375, compound → HCID 18172439, compound

HRID 397095Notes

Reaction equation

HRID 397095 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][N:11]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:12]([C:14]23[CH2:23][CH:18]4[CH2:19][CH:20]([CH2:22][CH:16]([CH2:17]4)[CH2:15]2)[CH2:21]3)=O)[CH:6]=[CH:7][CH:8]=1>CCOC(C)=O>[C:14]12([CH:12]3[C:6]4[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=4)[CH2:9][CH2:10][N:11]3[C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[CH2:15][CH:16]3[CH2:17][CH:18]([CH2:19][CH:20]([CH2:22]3)[CH2:21]1)[CH2:23]2

Participants

3

Reactant 1

HCID 90953375HCID 90953375, compound

Product 1

HCID 18172439HCID 18172439, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared by analogy to Preparation 65 except that adamantane-1-carboxylic acid [2-(3-methoxy-phenyl)-ethyl]-phenyl-amide was used instead of 4-methoxy-N-[2-(3-methoxy-phenyl)-ethyl]-N-phenyl-benzamide, and the final residue was subjected to flash chromatography using hexanes:EtOAc from 20:1 to 10:1.

Sources & evidence

ORD record
ord-c9f64f910c3641fe8b130c32a8c1b24d
Source dataset
uspto-grants-2003_08
Patent number
US06608203B2

Reaction notes

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