HCID 18172416, compound → HCID 18172388, compound

HRID 397097Notes

Reaction equation

HRID 397097 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][CH2:10][N:11]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[C:12](=O)[C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[CH:6]=[CH:7][CH:8]=1>CCOC(C)=O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][CH:8]=1)[CH:12]([C:13]1[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=1)[N:11]([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH2:10][CH2:9]2

Participants

3

Reactant 1

HCID 18172416HCID 18172416, compound

Product 1

HCID 18172388HCID 18172388, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared by analogy to Preparation 65 except that N-[2-(3-methoxy-phenyl)-ethyl]-N-phenyl-isonicotinamide was used instead of 4-methoxy-N-[2-(3-methoxy-phenyl)-ethyl]-N-phenyl-benzamide, and the final residue was subjected to flash chromatography using hexanes:EtOAc from 4:1 to 2:1.

Sources & evidence

ORD record
ord-33ad561759b1458da531bd1856a1a37b
Source dataset
uspto-grants-2003_08
Patent number
US06608203B2

Reaction notes

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