反应详情

A mixture of (4) (0.96 g, 4.61 mmol), dibenzoylperoxide (56 mg, 0.23 mmol) and N-bromosuccinimide (NBS) (0.82 g, 4.61 mmol) in carbon tetrachloride (20 ml) was heated at reflux for 20 hours. After cooling to room temperature and filteration the solvent was evaporated to-give a yellow oil. Flash chromatograph: silica, hexane/EtOAc (7:3) afforded the pure compound.

1. temperaturewas heated
2. temperatureat reflux for 20 hours
3. customfilteration the solvent was evaporated
4. customto-give a yellow oil