HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 4-Bromoethyl-isophthalic acid dimethylester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Reactant | 5-(Methoxycarbonyl)-2-methylbenzoic acid | HCID 22999486 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 4-Bromoethyl-isophthalic acid dimethylester | HCID 53753665 | — |
Reaction Steps
A mixture of (4) (0.96 g, 4.61 mmol), dibenzoylperoxide (56 mg, 0.23 mmol) and N-bromosuccinimide (NBS) (0.82 g, 4.61 mmol) in carbon tetrachloride (20 ml) was heated at reflux for 20 hours. After cooling to room temperature and filteration the solvent was evaporated to-give a yellow oil. Flash chromatograph: silica, hexane/EtOAc (7:3) afforded the pure compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610269B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-283f7ea7f3c2420ca4ccffc4d3095f59 |
| Source note | uspto-grants-2003_08 |