HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → HCID 69364178, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | CARBAMIC ACID, (3-FLUOROPHENYL)-, METHYL ESTER | HCID 3358980 | — |
| Reactant | CID 53628100 | HCID 178418400 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69364178 | HCID 69364178 | — |
Reaction Steps
The starting material (3-fluoro-2-iodo-phenyl)-carbamic acid methyl ester was prepared from (3-fluoro-phenyl)-carbamic acid methyl ester by double deprotonation with sec.butyllithium in tetrahydrofuran at −78° C. followed by reaction with iodine. m.p.:80-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610685B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-851486e0533a47ee84583327ef5d6ac7 |
| Source note | uspto-grants-2003_08 |