1-Methylpiperazine → HCID 178433259, compound

HRID 397390Notes

Reaction equation

HRID 397390 reaction equation
Cl[C:2]1[C:3]2[C:10](=[CH:11][C:12]3[NH:13][CH:14]=[N:15][C:16]=3[CH3:17])[C:9](=[O:18])[NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:19][N:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:17][C:16]1[N:15]=[CH:14][NH:13][C:12]=1[CH:11]=[C:10]1[C:3]2[C:2]([N:23]3[CH2:24][CH2:25][N:20]([CH3:19])[CH2:21][CH2:22]3)=[N:7][CH:6]=[N:5][C:4]=2[NH:8][C:9]1=[O:18]

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 178433258HCID 178433258, compound

Product 1

HCID 178433259HCID 178433259, compoundYield 49%

Procedure

The title compound (49% yield) was prepared from 4-chloro-5-(5-methyl-3H-imidazol-4-ylmethylene)-5,7-dihydro-pyrrolo[2,3-d]pyrimidin-6-one and 1-methylpiperazine according to the procedure described for Example 14. MS-EI 325 [M+].

Sources & evidence

ORD record
ord-4a2097e4beaf4d1bb6daff34e4a4a18c
Source dataset
uspto-grants-2003_08
Patent number
US06610688B2

Reaction notes

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