Hydroxyamine hydrochloride → HCID 59085925, compound

HRID 397674Notes

Reaction equation

HRID 397674 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]2[CH2:15][CH2:14][CH2:13][C@H:12]2[C:16]#[N:17])(=[O:10])=[O:9])=[CH:4][CH:3]=1.Cl.[NH2:19][OH:20]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([S:8]([N:11]2[CH2:15][CH2:14][CH2:13][C@H:12]2/[C:16](=[N:19]/[OH:20])/[NH2:17])(=[O:10])=[O:9])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 443297Hydroxyamine hydrochlorideHCID 57035411HCID 57035411, compound

Product 1

HCID 59085925HCID 59085925, compound

Procedure

The title compound was prepared by the method of Preparation 4 from (2S)-1-[(4-fluorophenyl)sulfonyl]-2-pyrrolidinecarbonitrile [see Preparation 51] and hydroxylamine hydrochloride to afford the title compound as a white solid.

Sources & evidence

ORD record
ord-bce75533d8484c68b886c15035ae90a0
Source dataset
uspto-grants-2003_08
Patent number
US06610707B1

Reaction notes

Loading…