HRID397695

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2735644

未命名化合物

$结构：N/C(=N\O)[C@@H]1CCCCN1S(=O)(=O)CC1CCCCC1$

HCID59085897

未命名化合物

PRODUCTS

生成物

$结构：CC(C)(C)OC(=O)N1CCN(CCC(=O)O/N=C(\N)[C@@H]2CCCCN2S(=O)(=O)CC2CCCCC2)CC1$

HCID59085906

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by a similar method to Preparation 5 from (Z)-(2S)-1-[cyclohexylmethylsulfonyl]-N′2-hydroxy-2-piperidinecarboximidamide [see Preparation 28] and 3-[4-(tert-butoxycarbonyl)piperazino]propanoic acid [see Preparation 90] to afford tert-butyl 4-(3-[((Z)-amino(2S)-1-[(cyclohexylmethyl)sulfonyl]-2-piperidylmethylidene)amino]oxy-3-oxopropyl)-1-piperazinecarboxylate as a brown oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-fb5f74dc90f64219ad09c9b9ec2b5ca7
来源数据集: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06610707B1
来源说明: uspto-grants-2003_08

反应 SMILES

[CH:1]1([CH2:7][S:8]([N:11]2[CH2:16][CH2:15][CH2:14][CH2:13][C@H:12]2/[C:17](=[N:19]/[OH:20])/[NH2:18])(=[O:10])=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:21]([O:25][C:26]([N:28]1[CH2:33][CH2:32][N:31]([CH2:34][CH2:35][C:36](O)=[O:37])[CH2:30][CH2:29]1)=[O:27])([CH3:24])([CH3:23])[CH3:22]>>[NH2:18]/[C:17](=[N:19]\[O:20][C:36](=[O:37])[CH2:35][CH2:34][N:31]1[CH2:32][CH2:33][N:28]([C:26]([O:25][C:21]([CH3:23])([CH3:22])[CH3:24])=[O:27])[CH2:29][CH2:30]1)/[C@@H:12]1[CH2:13][CH2:14][CH2:15][CH2:16][N:11]1[S:8]([CH2:7][CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1)(=[O:9])=[O:10]