2-Chlorophenol → HCID 131724044, compound

HRID 397813Notes

Reaction equation

C1(C(C2C=CC=CC=2)(C2C=CC=CC=2)[N:8]2[C:12]3[CH2:13][CH2:14][CH2:15][CH2:16][CH:17]([CH2:18][OH:19])[C:11]=3[N:10]=[CH:9]2)C=CC=CC=1.[Cl:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1O>>[ClH:32].[Cl:32][C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][C:34]=1[O:19][CH2:18][CH:17]1[C:11]2[N:10]=[CH:9][NH:8][C:12]=2[CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

Reactant 2

HCID 72452-Chlorophenol

HCID 23001236HCID 23001236, compound

Product 1

HCID 131724044HCID 131724044, compound

Procedure

Using a procedure similar to that described in Example 22 and starting from (1-triphenylmethyl-1,4,5,6,7,8-hexahydrocycloheptaimidazole-4-yl)methanol (0.20 g, 0.49 mmol) and 2-chlorophenol (0.1 ml, 1 mmol) 94 mg (61%) of the title compound was obtained as a solid.

Sources & evidence

ORD record: ord-84b28d5e6163460799faa72129d94d3b
Source dataset: uspto-grants-2003_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06610721B2

Reaction notes

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