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HRID 397881作成日:2026年10月25日

2-(4-Chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Chloro-3-trifluoromethyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine Hydrochloride

https://huagongshe.com/reaction/397881

反応式

関与物質

役割名称HCID仕込み量
反応物2-(4-Chloro-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 17750238—
反応物3-Bromo-5-(2-methyl-imidazol-1-ylmethyl)-pyridineHCID 23444965—
生成物3-(4-Chloro-3-trifluoromethyl-phenyl)-5-(2-methyl-imidazol-1-yl-methyl)-pyridine HydrochlorideHCID 23445051—

反応手順

The title compound, MS: m/e=352.3 (M+H+) was obtained as a beige foam (49% yield) by the reaction of 3-bromo-5-(2-methyl-imidazol-1-yl-methyl)-pyridine with 2-(4-chloro-3-trifluoromethyl-phenyl)-4,4,5,5-tetramethyl-[1,3,2] dioxaborolane.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06610723B2
出典データセットuspto-grants-2003_08
ORD IDord-3f901ff0844f49e38a2f77348cefa166
出典メモuspto-grants-2003_08