HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Fluorophenyl)-1,3-propanediamine → 2-Chloro-5-(4-fluorophenyl)-4-(4-pyridyl)-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Fluorophenyl)-1,3-propanediamine | HCID 22346576 | — |
| Reactant | 2-Chloro-4-(4-pyridyl)-5-(3-trifluoromethylphenyl)-pyrimidine | HCID 53843035 | — |
| Product | 2-Chloro-5-(4-fluorophenyl)-4-(4-pyridyl)-pyrimidine | HCID 23000365 | — |
Reaction Steps
2-Chloro-4-(4-pyridyl)-5-(3-trifluoromethylphenyl)-pyrimidine and 1-(2-fluorophenyl)-1,3-propanediamine were reacted according to the General Procedure, Step C (100° C. for 30 min) to give the title compound. MS (m/z): 468.4 (M+H)+; C25H21F4N5 requir. 467.5 (free base).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610698B2 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-8a3a36f06a9441a8bacf16297ef0f063 |
| Source note | uspto-grants-2003_08 |