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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 398343Generated: October 30, 2026

HCID 23000277, compound → 4-Methyl-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile

https://huagongshe.com/reaction/398343

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23000277HCID 23000277—
CatalystHCID 178418406HCID 178418406—
SolventChloroformHCID 6212—
Product4-Methyl-1H-pyrrolo[2,3-b]pyridine-5-carbonitrileHCID 23000237—

Reaction Steps

A mixture of 5-cyano-4-methyl-7-azaindoline (52 mg, 0.33 mmol) and manganese dioxide (130 mg, 1.5 mmol) in chloroform (10 mL) was stirred for 16 h and then was filtered through celite, washing through with chloroform followed by methanol. The filtrate was evaporated in vacuo to give the title compound as a tan solid:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06610692B1
Source datasetuspto-grants-2003_08
ORD IDord-dd8fbfc54c8a4cd68855d8c458a08a9c
Source noteuspto-grants-2003_08