反应详情

5-Cyano-2-fluorobenzaldehyde (512 mg, 3.43 mmol) was dissolved in hydrazine hydrate (25 mL) at room temperature and the solution left to stand overnight. To this reaction mixture was added methylene chloride (30 mL). The mixture was purified by filtration through a pad of silica eluting with methylene chloride, concentrated in vacuo to afford a white solid:

1. waitthe solution left
2. filtrationThe mixture was purified by filtration through a pad of silica eluting with methylene chloride
3. concentrationconcentrated in vacuo
4. customto afford a white solid