HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Difluoro-2-(2-pyridyl)ethylazide → 2,2-Difluoro-2-pyridin-2-ylethaneamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Difluoro-2-(2-pyridyl)ethylazide | HCID 11805405 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 2,2-Difluoro-2-pyridin-2-ylethaneamine | HCID 9964167 | — |
Reaction Steps
A stirred solution of 100 mg of 2,2-difluoro-2-(2-pyridyl)ethylazide was hydrogenated in 10 mL of ethyl acetate over 100 mg of 10% palladium on carbon using a balloon for 1 h. The catalyst was removed by filtration and the solvents removed at reduced pressure to give the title compound as a yellow oil:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06610692B1 |
| Source dataset | uspto-grants-2003_08 |
| ORD ID | ord-d44c3debdee54d528ae653270d56a3de |
| Source note | uspto-grants-2003_08 |