Acetic Anhydride → HCID 18969122, compound

Participants

Reaction Steps

An acetic anhydride solution (20 ml) of 1.5 g of 3-cyclohexylcarbonyl-2-ethylaminopyridine was heated under reflux for 4 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (toluene-ethyl acetate) to give 1.1 g of N-(3-cyclohexylcarbonyl-2-pyridyl) -N-ethylacetamide.

Provenance & Evidence