反应详情

(1)-2 A mixture of 2,6-dichloronicotinic acid (50.6 g) with thionyl chloride (100 ml) was refluxed for 2 hours. The excess thionyl chloride was distilled off under reduced pressure, and crude product was distilled under reduced pressure to give 2,6-dichloronicotinoyl chloride (44.9 g).

1. temperaturewas refluxed for 2 hours
2. distillationThe excess thionyl chloride was distilled off under reduced pressure, and crude product
3. distillationwas distilled under reduced pressure