HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2,6-Dichlorpyridine-3-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2,6-Dichloronicotinic acid | HCID 854047 | — |
| Product | 2,6-Dichlorpyridine-3-carbonyl chloride | HCID 12263984 | — |
Reaction Steps
(1)-2 A mixture of 2,6-dichloronicotinic acid (50.6 g) with thionyl chloride (100 ml) was refluxed for 2 hours. The excess thionyl chloride was distilled off under reduced pressure, and crude product was distilled under reduced pressure to give 2,6-dichloronicotinoyl chloride (44.9 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817669 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-f1c0d6bdb2d04c7984643587a80f488d |
| Source note | uspto-grants-1998_10 |