5-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine → HCID 19601615, compound

HRID 398936Notes

Reaction equation

HRID 398936 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([CH:11]3[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.Cl.[N:20]1[CH:25]=[CH:24][C:23]([C:26](Cl)=[O:27])=[CH:22][CH:21]=1>>[N:20]1[CH:25]=[CH:24][C:23]([C:26]([NH:1][C:2]2[N:7]=[C:6]3[C:8]([CH:11]4[CH2:16][CH2:15][N:14]([CH2:17][CH3:18])[CH2:13][CH2:12]4)=[CH:9][NH:10][C:5]3=[CH:4][CH:3]=2)=[O:27])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 117706865-Amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridineHCID 12262826Isonicotinoyl chloride hydrochloride

Product 1

HCID 19601615HCID 19601615, compound

Procedure

Beginning with 0.015 gm (0.061 mMol) 5-amino-3-(1-ethylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.014 gm (0.080 mMol) 4-pyridinecarbonyl chloride hydrochloride, the title compound was prepared essentially by the procedure described in Example 7.

Sources & evidence

ORD record
ord-d30b81e55f764ef6bba29b9c2c0893ca
Source dataset
uspto-grants-1998_10
Patent number
US05817671

Reaction notes

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