Hydrochloric Acid → HCID 178505135, compound

HRID 398986Notes

Reaction equation

C([O:5][C:6]([CH2:8][N:9]([C@H:14]1[CH2:19][CH2:18][C@H:17]([C:20]([NH:22][C:23]2[N:24]=[CH:25][N:26]([CH:28]3[CH2:33][CH2:32][N:31](C(OC(C)(C)C)=O)[CH2:30][CH2:29]3)[CH:27]=2)=[O:21])[CH2:16][CH2:15]1)[S:10]([CH3:13])(=[O:12])=[O:11])=[O:7])(C)(C)C.[ClH:41]>>[ClH:41].[ClH:41].[C:6]([CH2:8][N:9]([C@H:14]1[CH2:15][CH2:16][C@H:17]([C:20]([NH:22][C:23]2[N:24]=[CH:25][N:26]([CH:28]3[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]3)[CH:27]=2)=[O:21])[CH2:18][CH2:19]1)[S:10]([CH3:13])(=[O:11])=[O:12])([OH:7])=[O:5]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 178451270HCID 178451270, compound

Product 1

HCID 178505135HCID 178505135, compound

Procedure

4-[[trans-4-(N-tert-Butoxycarbonylmethyl-N-methanesulphonyl-amino)cyclohexyl]carbonylamino]-1-(1-tert-butoxycarbonyl-4-piperidyl)imidazole is employed. By dissolving in 1N hydrochloric acid and evaporating the solvent, the hydrochloride is prepared.

Workup

customevaporating the solvent

Sources & evidence

ORD record: ord-230f7ceb3ca2430a8debe37cf30b1e9c
Source dataset: uspto-grants-1998_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05817677

Reaction notes

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