HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[(2-Butyl-4-quinolinyl)-amino]benzoic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Aminobenzoic Acid | HCID 978 | — |
| Reactant | 2-Butyl-4-chloroquinoline | HCID 11042235 | — |
| Product | 4-[(2-Butyl-4-quinolinyl)-amino]benzoic acid hydrochloride | HCID 67603346 | 60.8% |
Reaction Steps
0.840 g of the product of Step D of Example 3 and 0.640 g of amino benzoic acid were introduced into 15 ml of 1N hydrochloric acid and the solution was refluxed for 3 hours. The precipitate was filtered, washed with water and dried at 60° C. under reduced pressure to obtain 0.830 g of the expected product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817674 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-29533e97c15246aea3382b863fc614c2 |
| Source note | uspto-grants-1998_10 |