Phosphorus oxychloride → HCID 19595374, compound

HRID 398994Notes

Reaction equation

HRID 398994 reaction equation
[CH2:1]([C:5]1[N:6]=[N:7][C:8]2[C:13]([C:14]=1O)=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:2][CH2:3][CH3:4].P(Cl)(Cl)([Cl:18])=O>>[CH2:1]([C:5]1[N:6]=[N:7][C:8]2[C:13]([C:14]=1[Cl:18])=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 178441902HCID 178441902, compound

Product 1

HCID 19595374HCID 19595374, compound

Procedure

Using the procedure of Step F of Example 1, 1.2 g of the product of Step B and 10 ml of phosphorous oxychloride were reacted to obtain after chromatography on silica (eluant:hexane-ethyl acetate (6.4)), 1.16 g of the desired product melting at <50° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-853fb93278a248d28d5cf1495ff63e1f
Source dataset
uspto-grants-1998_10
Patent number
US05817674

Reaction notes

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