4-(Bromomethyl)benzonitrile → 4-[[(3-Butyl-4-cinnolinyl)-oxy]-methyl]benzonitrile

HRID 398995Notes

Reaction equation

HRID 398995 reaction equation
[CH2:1]([C:5]1[N:6]=[N:7][C:8]2[C:13]([C:14]=1[OH:15])=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:2][CH2:3][CH3:4].Br[CH2:17][C:18]1[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][CH:19]=1>>[CH2:1]([C:5]1[N:6]=[N:7][C:8]2[C:13]([C:14]=1[O:15][CH2:17][C:18]1[CH:25]=[CH:24][C:21]([C:22]#[N:23])=[CH:20][CH:19]=1)=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 869964-(Bromomethyl)benzonitrileHCID 178441902HCID 178441902, compound

Product 1

HCID 195953714-[[(3-Butyl-4-cinnolinyl)-oxy]-methyl]benzonitrile

Procedure

Using the procedure of Example 6, the product of Step B of Example 13 and 4-(bromomethyl)benzonitrile were reacted to obtain the desired product.

Sources & evidence

ORD record
ord-58836421c42b453db5e6008ce92ec1e1
Source dataset
uspto-grants-1998_10
Patent number
US05817674

Reaction notes

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