HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-dihydroisoquinoline → HCID 10592220, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-dihydroisoquinoline | HCID 422511 | — |
| Reactant | HCID 10704607 | HCID 10704607 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 10592220 | HCID 10592220 | 45% |
Reaction Steps
4-(2-Chloroethoxy)-7-fluoro-1,3-dihydro-indol-2-one was reacted with dihydroisoquinoline in anhydrous dimethyl sulfoxide in the same manner described for intermediate 16 to afford the title compound in 45% yield. The fumarate salt was made in ethanol: mp 230°-235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817690 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-9b8aebd8fa6b4dc89d05c177aef8c17c |
| Source note | uspto-grants-1998_10 |