HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → (3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yloxy)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 11373418 | HCID 11373418 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (3-{2-[(R)-2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-1H-indol-7-yloxy)-acetic acid | HCID 6916441 | — |
Reaction Steps
The compound obtained in Example 14 and sodium hydroxide are added to an aqueous methanol solution (methanol/water=2:1), and the mixture is treated in the same manner as in Example 13 to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05817689 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-3731a555d3734aa1856e8901a5779538 |
| Source note | uspto-grants-1998_10 |