Water → 2-(p-Chlorophenyl)-4-[(3,4-dichlorophenyl)sulfonyl]-5-(trifluoromethyl)pyrrole-3-carbonitrile

Participants

Reaction Conditions

Reaction Steps

A solution of 2-(p-chlorophenyl)-4-[(3,4-dichlorophenyl)thio]-5-(trifluoromethyl)pyrrole-3-carbonitrile (1.0 g, 2.2 mmol) in methanol is treated with a solution of potassium peroxymonosulfate (2.95 g) in water (7.4 mL), stirred at 25° C. for 24 hours, diluted with additional methanol, treated with a solution of potassium peroxymonosulfate (2.7 g) in water (7.6 mL), stirred at 25° C. for 24 hours, and filtered to obtain a solid which is washed with water and dried to give the title product a white solid (mp >225° C.).

Provenance & Evidence