Hydrogen Peroxide → HCID 18969595, compound

HRID 399039Notes

Reaction equation

HRID 399039 reaction equation
[Cl:1][C:2]1[C:6]([S:7]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[O:8])=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[NH:4][C:3]=1[C:22]([F:25])([F:24])[F:23].[OH:26]O>C(O)(=O)C>[Cl:1][C:2]1[C:6]([S:7]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)(=[O:26])=[O:8])=[C:5]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[NH:4][C:3]=1[C:22]([F:24])([F:23])[F:25]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 18969603HCID 18969603, compound

Product 1

HCID 18969595HCID 18969595, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
50 °C

Procedure

A mixture of 3-chloro-5-(p-chlorophenyl)-4-(phenylsulfinyl)-2-(trifluoromethyl)pyrrole (0.335 g, 0.83 mmol) and 30% hydrogen peroxide solution (0.28 mL, 2.49 mmol) in acetic acid is stirred at 50° C. for 7 hours, cooled and poured into an ice-water mixture. The resultant aqueous mixture is filtered to obtain a solid which is washed with water and dried to give the title product as a colorless solid (mp 158°-161° C.).

Workup

  1. temperaturecooled
  2. filtrationThe resultant aqueous mixture is filtered
  3. customto obtain a solid which
  4. washis washed with water
  5. customdried

Sources & evidence

ORD record
ord-2dad116afb6140169d0c07f02b43e795
Source dataset
uspto-grants-1998_10
Patent number
US05817691

Reaction notes

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